BINAP Silver I -Catalyzed Asymmetric Reactions

In 1996 Yanagisawa, Yamamoto, and their colleagues first reported the asymmetric allylation of aldehydes with allylic stannanes catalyzed by a BINAP silver(I) complex [29]. The chiral phosphine-silver(I) catalyst can be prepared simply by stirring an equimolar mixture of BINAP and silver(I) compound in THF at room tempera- 

Determined by HPLC analysis with chiral columns. 

4 equiv. allyltributyltin (68) and 0.2 equiv. (5)-BINAP AgOTf was used. 

Condensation of )/-substituted allylmetals with aldehydes is a fascinating subject with regard to regioselectivity (a/y) and stereoselectivity ElZ or antilsyn). Addition of ( )-crotyltributyltin (70E, ElZ = 95/5) to benzaldehyde in the presence of 

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