Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

BINAP ligand primary arylamines

Arylamines. Primary," secondary, and tertiary arylamines have been prepared by Pd(0)-catalyzed IV-arylation methods. The most common and effective catalytic system contains (dbaljPd, r-BuONa, and a tertiary phosphine such as BINAP. The nucleophilic species for the synthesis of primary anilines is a Ti-N complex formed from (i-PrO) Ti, Li, and McjSiCl in THF under nitrogen at room temperature (8 h). N-Arylation of chiral secondary amines proceeds without affecting the stereocenters. Arylation with Arl is facile because it can be carried out at room temperature. More recent development indicates that employment of 2-dimethylamino-2 -dicyclohexylphosphinobiphenyl as ligand in the amination of unactivated chloroarenes under mild conditions is also possible. [Pg.419]

See other pages where BINAP ligand primary arylamines is mentioned: [Pg.478]    [Pg.1055]    [Pg.1065]    [Pg.1055]    [Pg.1065]    [Pg.80]    [Pg.212]    [Pg.239]    [Pg.474]    [Pg.575]    [Pg.576]    [Pg.1062]    [Pg.1075]    [Pg.1062]    [Pg.1075]   
See also in sourсe #XX -- [ Pg.1065 , Pg.1066 ]



SEARCH



Arylamin

Arylamination

Arylamine

Arylamines

BINAP

BINAPs

Ligand, BINAP

© 2024 chempedia.info