Bile-acid overview synthesis

An Overview of Bile-Acid Synthesis, Chemistry and Function... 

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Fig. 1. Overview of the metabolic and transport pathways that control cholesterol levels in mammalian cells. Cholesterol is synthesized from acetyl-CoA and the four key enzymes that regulate cholesterol synthesis are indicated. Cells also obtain cholesterol by uptake and hydrolysis of LDL s cholesteryi esters (CE). End products derived from cholesterol or intermediates in the pathway include bile acids, oxysterols, cholesteryi esters, and non-steroidal isoprenoids. ACAT, acyl-CoA cholesterol acyltransferase.

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