Bibliography on Arginase

TJebet einige Hefefermente, Zeits. f. physiol. Chem., 1904, (42), p. 303. Daeim. The action of arginase upon Creatin and other Guanidin derivatives, Jmm. of Biol. Chem., 1907, (3), p. 435. 

By stud)dn.g the auto-digestion of muscular juice, we find immediately an increase of the creatin, an increase which results from the splitting of certain nitrogenous compounds whose evolution we cannot, moreover, very well foUow. However, the creatin formed does not accumulate in the liquid, but progressively disappears. This is due to the fact that the creatin present is transformed into creatinin, and that these two compounds, creatin and creatinin, are then decomposed in a more complete manner in consequence of the action of certain biochemical agents. 

we find first an increase in the quantity of creatin present, since after 114 hours we measure 23.0 — 4.1 = 18.9 mg, of this body, in place of 19.2 — 2.8 = 16.4 mg. measured at the beginning. But this quantity then diminishes to produce creatinin, whose proportion will increase. Furthermore, the creatin, and even the creatinin, will be destroyed in another way, since the sum of these two substances grows smaller. The transitory increase in the content in creatin, and the ultimate destruction of the creatin and the creatinin can be better shown if creatin is added to muscular juice. 

The chemical reaction accelerated by creatino-creatase is expressed by the following equation  

According to Gottlieb and Stangasdnger, in the disappearance of creatin three different enzjnnes intervene Ihe one just described, which transforms creatin into creatinin, and then two 

---