Biaryl diamides

In 2003, O Shaughnessy and Scott reported the first example of rare-earth metal complexes supported by biaryl diamide ligands as the catalysts for the hydroamination reactions [159]. A series of C2 symmetric secondary diamine proligands L37-L40 were prepared by arylations of (7 )-2,2 -diamino-6,6 -dimethybiphenyl under palladium catalysis. L37 reacted with complexes [Ln N(SiHMe2)2 3(THF)2] to form the biaryl diamide complexes [Ln(L37) N(SiHMe2)2 (THF)2] (Ln = Y (190), La (191), Sm (192)). Deprotonation... 

In the same year, the first structurally defined biaryl diamide complexes as enantioselective intramolecular hydroamination catalysts were reported by Schulz and coworkers. They are the first example of lanthanide catalysts supported by a binaphthyl diamide ligand. 2 equiv of the lithium salt of the binaphthyl diamide ligand Li2L41 and anhydrous LnCls in THF at ambient temperature generated ate complexes [Li(THF)4][Ln(L41)2] (Ln = Sm 197 and Yb 198) via salt elimination (Scheme 76). 

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