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3- Benzyloxy-2-pyrazinamine

Chloro-2-pyrazinamine (121, R = Cl) gave 3-benzyloxy-2-pyrazinamine (121, R = OCH2Ph) (PhCH2ONa, PhCH2OH, warmed , 72 h 58% sometimes accompanied by a separable byproduct, 2-benzylamino-3-benzy-loxypyrazine (122), in small amount.1567, cf-616... [Pg.161]

Dibromo-2-pyrazinamine (123, R = Br) gave 3-benzyloxy-5-bromo-2-pyrazinamine (123, R = OCH2Ph) (PHCH2ONa, PhCH2OH, reflux, 4 h 51%) 661 also analogues likewise.661 Also other examples.1012 1198... [Pg.161]

Ethyl 3-amino-6-benzyloxy-5-isobutyl-2-pyrazinecarboxylate 4-oxide (120, R = C02Et) gave 5-benzyloxy-3-hydroxymethyl-6-isobutyl-2-pyrazinamine 1-oxide (120, R = CH2OH) (Bu 2A1H, CHC13—C6H14, 3°C, 45 min 65%).848... [Pg.209]

Benzyloxy-2-pyrazinamine 6-Benzyloxy-2-pyrazinecarbonitrile 6-Benzyloxy-2-pyrazinecarboxylic... [Pg.373]

Benzyloxy-3-hydroxymethyl-6-isobutyl-2-pyrazinamine 1-oxide (57, R = CH2OH) gave 2-benzyloxy-5-chloro-6-hydroxymethyl-3-isobutylpyrazine 4-oxide (58, R = ( 111 )11) (Bu CHjONO, CuCl—CuCli, N2, MeCN, 20°C, 30 min 75%) " and methyl 3-amino-6-benzyloxy-5-isobutyl-2-pyrazinecar-boxylate 4-oxide (57, R = CO2Me) gave methyl 6-benzyloxy-3-chloro-5-isobutyl-2-pyrazinecarboxylate 4-oxide (58, R = CO2Me) (likewise but 90 min 61%) ... [Pg.147]

See other pages where 3- Benzyloxy-2-pyrazinamine is mentioned: [Pg.373]    [Pg.147]    [Pg.372]    [Pg.373]    [Pg.373]    [Pg.372]    [Pg.373]   
See also in sourсe #XX -- [ Pg.161 ]

See also in sourсe #XX -- [ Pg.161 ]



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