2- Benzyloxy-6-chloropyrazine

Benzyloxy-6-chloropyrazine 2-Benzyloxy-3,6-diisobutyl-5-methoxypyrazine 2-Benzyloxy-3,6-diisobutyl-5-methoxypyrazine 1-oxide 2-Benzyloxy-3,6-diisobutyl-5-methoxypyrazine 4-oxide... 

Benzyloxy-6-chloropyrazine with Z.SN sodium hydroxide in aqueous ethanol at reflux gave a mixture from which 2-benzyloxy-6-ethoxypyrazine and other... 

Other hydrolyses with sodium hydroxide have been described as follows. 2-Benzyloxy-6-chloropyrazine in ethanol with 3.5N sodium hydroxide at reflux for 4.5 hours gave 2-chloro-6-hydroxypyrazine (832), 2-chloro-6-metho)Qrpyrazine with aqueous ethanolic sodium hydroxide gave 2-chloro-6-hydroxypyrazine (43%) possibly containing a small amount of 2-hydroxy-6-methoxypyrazine) (883), and 2,6-dimethoxypyrazine with aqueous ethanolic sodium hydroxide at reflux for 24 hours formed 2-hydroxy-6-methoxypyrazine (832). 

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