Benzoxazinones, solution-phase

Finally, a five-step solution phase synthesis of benzoxazinones used a combination of reactant-sequestering resins, a bifunctional linking reagent, a polymer-supported reagent, and solid-phase quench for synthesis and purification (Scheme 14)22 This features... 

The synthesis of a 35-member, solution-phase benzoxazinone library L18 using a five-step synthetic scheme with intermediate purifications that employed supported... 

Figure 8.36 Synthesis of the solution-phase, discrete benzoxazinone library L18 and structure of the monomer sets Mi-M2.

Figure 8.37 Synthesis and purification of the solution-phase discrete benzoxazinone library L16 amine acylation and synthesis of 8.72.

SYNTHETIC ORGANIC LIBRARIES SOLUTION-PHASE LIBRARIES TABLE 8.4 Yields and purity of the benzoxazinone discrete library L18... 

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