Benzimidazole 2-trichloromethyl

Benzimidazole, l-methyl-2-trichloromethyl-substitution reactions, 5, 432 Benzimidazole, naphthoyl-, 1, 327 Benzimidazole, 5-nitro-alkylation, 5, 390 Benzimidazole, 6-nitro-1-oxide... 

Benzimidazole with [Cr(CO)5CNCCl3] gives the A, A -earbenes 109 and 110, the produets of simultaneous attack at trichloromethyl and isocyano groups simultaneously (95JOM(489)27). The probability of the formation of the primary product [Cr(CO)5(C(L)N=CCl2] is low (88AGE1344, 89ZN(B)1414). 

Imidazoles react with chloroform at high temperature to form azines by carbene insertion and trichloromethyl radicals behave similarly, but carbenes do not always induce ring expansion. In alkaline medium, chlorodifluoromethane converts benzimidazole and its 2-methyl analogue into the 1-difluoromethyl derivatives 365. Dichlorocarbene under basic conditions N-alkylates benzimidazole, and 1-methylbenzimidazole couples under the influence of the same reagent (Scheme 69), perhaps involving initial attack of the carbene at N(3). 

Benomyl commercial fungicide, methyl l-(butylcarbamoyl)-benzimidazol-2-ylcarbamate. Captan commercial fungicide, N-[(trichloromethyl)thio]cyclohex-4-ene-l,2-dicarboximide. 

In 2-substituted benzimidazoles the chloromethyl and cyanomethyl derivatives have lowest energy transitions of the n-n type but those of 5-chloro-2-trichloromethyl-, 2-trifiuoromethyl-, and 2-chloro-benzimidazoles are of the charge-transfer type. In the corresponding monocations and monoanions the lowest energy transitions are charge transfer and n-n respectively. The presence of a methylene group between the heterocycle and the exocyclic heteroatom reduces direct interactions <87JCS(P2)1465>. 

Proprietary cross linker Rubber to metal bonding agent 4,4 Dithio-bis-morphoUne 2-Mercaptotolulimidazole Zinc 2-mercapto-toluimidazole 4- and 5-Methyhnercapto benzimidazole—oil treated Al-(trichloromethyl sulfenyl)-Benzene suhbne anilide,... 

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