Benzenoid Compounds identification

Korany et al. [28] used Fourier descriptors for the spectrophotometric identification of miconazole and 11 different benzenoid compounds. Fourier descriptor values computed from spectrophotometric measurements were used to compute a purity index. The Fourier descriptors calculated for a set of absorbencies are independent of concentration and is sensitive to the presence of interferents. Such condition was proven by calculating the Fourier descriptor for pure and degraded benzylpenicillin. Absorbance data were measured and recorded for miconazole and for all the 11 compounds. The calculated Fourier descriptor value for these compounds showed significant discrimination between them. Moreover, the reproducibility of the Fourier descriptors was tested by measurement over several successive days and the relative standard deviation obtained was less than 2%. 

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