Basic Qualities of a Good QSAR Model

The development oi a quantitative SAR model implies that the model should be testable and verifiable. The criteria outlined below, given as a critical tool for QSAR-based research, 124,129 ju y, gip end usef in the meta-analy- 

Relevance Closely associated with explanatory power is the pharmacological (mechanistic) relevance of the descriptor fields used in a 3D-QSAR model. As additional fields become available as 3D-QSAR descriptors, caution must exercised in the application of a particular field to the problem at hand. This is directly analogous to the problem of choosing appropriate descriptors in classical QSAR. 

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