Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Barbiturates GABAergic function

The pharmacological effects of the barbiturates is invariably marked by a decrease with regard to the normal functional activities in the brain. It has been duly observed that at the prevailing therapeutic dose levels in vivo the barbiturates cause a distinct marked enhancement of the GABAergic inhibitory response, in a mechanism very much akin to that shown by the benzodiazepines, that is, by influencing conductance at the site of chloride channel. It is pertinent to mention here that at comparatively higher concentration barbiturates would display six marked and pronounced pharmacological actions ... [Pg.194]

The effects of the barbiturates is marked by a decrease in functional activities in the brain. At therapeutic doses, the barbiturates enhance the GABAergic inhibitory response in a mechanism similar to that of the... [Pg.750]

See other pages where Barbiturates GABAergic function is mentioned: [Pg.75]    [Pg.229]    [Pg.409]    [Pg.237]    [Pg.462]    [Pg.297]    [Pg.86]    [Pg.95]    [Pg.592]    [Pg.409]   
See also in sourсe #XX -- [ Pg.291 ]



SEARCH



Barbiturics

GABAergic

© 2024 chempedia.info