Band-broadening/-focusing mechanisms

Two models of two-dimensional band broadening were established by Belenky et al. and by Mierzejewski. In these models, nonlinearity of the adsorption isotherm was neglected so that elliptical spots only, with symmetrically distributed concentration (as shown in Fig. la), could be modeled. We will now focus our attention on the effect of the adsorption mechanism on the concentration profiles of chromatographic bands. 

In the absence of a focusing mechanism the slow introduction of sample into the column causes all solute bands to be broadened equally. Figure 3.10. This band broadening in time is minimized by temporarily increasing the retention power of the column... 

Overview of the Instrumentation Band-Broadening and Band-Focusing Mechanisms Setting the Temperatures Setting the Flows and Purge off Time Optimization Recommendations... 

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