Azoxy compounds reductive cleavage

Dinitrogen moieties are also targets of oxi-doreductases. Depending on their substituents, hydrazines are oxidized to azo compounds (reaction 7-A), some of which can be oxygenated to azoxy compounds (reaction 1-D). Another important pathway of hydrazines is their reductive cleavage to primary amines (reaction 7-C). Reactions 7-A and 7-D are reversible and the corresponding reduc-... 

Af-oxides back to the amine (see Fig. 31.25). The same is true for aromatic nitro compounds, aromatic nitroso compounds and hydroxylamines, and imines and oximes, which can ultimately be reduced to primary amines. Azo and azoxy compounds can be reduced to hydrazines. An important pathway of hydrazines is their reductive cleavage to primary amines. A toxicologically significant pathway thus exists for the reduction of some aromatic azo compounds to potentially toxic prUnary aromatic amines. 

Oxidative cleavage of amines 9-39 Reduction of amides 9-47 Reduction of nitro compounds 9-50 Reduction of nitroso compounds or hydroxylamincs 9-51 Reduction of oximes 9-52 Reduction of azides 9-53 Reduction of isocyanates, isothiocyanates, or N-nitroso compounds 9-55 Reduction of amine oxides 9-59 Reduction of azo, azoxy, or hydrazo compounds... 

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