Azoles reaction

Pyrimido[4,5-6]quinolinium salts pseudo bases - ring opening, 3, 208 Pyrimido[4,5-6]quinolinium salts, 4-chloro-hydrolysis, 3, 214 Pyrimido[4,5-6]quinolinones synthesis, 3, 228 Pyrimido[4,5 -6]quinolin-5-ones synthesis, 3, 221-222 Pyrimidothiadi azoles reactions, 6, 533 Pyrimidothiazines synthesis, 4, 527 Pyrimidothiazinones mass spectra, 2, 23... 

Figure 27.6 The 5 -phosphate group of oligonucleotides may be labeled with cystamine using the EDC/imid-azole reaction. This results in the formation of an amine-terminal spacer containing an internal disulfide group. Reduction of the disulfide provides a route to creating a free thiol for further derivatization.

Sulphonyl group Azole Reaction conditions % yield... 

Katritzky, A. R. Li, J. Malhotra, N. N-Vinyl, N-allyl, N-propenyl and N-propargylbenzotri-azoles reactions of their lithium derivatives. Liebigs Ann. Chem. 1992, 843—853. 

The mutual transitions of various types of hetero cycles (recyclizations) are fairly widespread in the chemistry of azoles. Reaction of 1,4-dinitropyrazole with hydrox-ylamine liberated from corresponding salt in the presence of sodium methoxide resulted in 4-nitroisoxazole (77%) and a small amount of 5-methoxy-4-nitropyrazole [535], 4-Nitroisoxazoles, like incidentally their unnitrated analogs, are transformed into derivatives of 4-nitropyrazole by the hydrazine or its monosubstituted derivatives. Thus, 3(5)-amino-5(3)-methyl-4-nitropyrazole or its 1-organo derivative was obtained from 5-methyl-4-nitroisoxazole [28, 34, 35, 536] (Scheme 92). 

Chloromethyl-1,3-azoles, reactions with sulfur 88ZC233. Diazoazoles 90AHC(48)66. 

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