Aziridinyl-amino substituted cyclophosphazenes

Aziridinyl-amino derivatives of (NPCl2)3 and (NPCl2)4 can be prepared by the aminolysis of the appropriate 1-aziridinyl-chloro precursors. An alternative possibility is offered by the reaction of compounds N3P3Am Q or N4P4Amg Cl (Am = amino) with an excess of aziridine. Both routes provide comparable yields. The choice between them is governed by the accessibility of the precursor. 

CYCLOTRIPHOSPHAZENE [c/s- AND /raits-2,4,-BIS(l-AZIRIDINYL)-2,4,6,6-TETRAiaS(METHYLAMINO)-l,3,5,2X 4X 6X -TRIAZATRIPHOSPHORINE AND 2,2-BIS(l-AZIRIDINYL)-4,4,6,6-TETRAKIS(METHYLAMINO)-l,3,5,2XS4XS6X -TRIAZATRIPHOSPHORINE] 

The reactions should be carried out in a dry nitrogen atmosphere in order to avoid hydrolysis of partially aminolyzed products. 

Fraction 1. 1.50 g of a white solid recrystallization from hexane yields 

Fraction 3. 1.86 g of a white solid recrystallization from an hexane-diethyl ether mixture yields 1.43 g (3.96 mmol = 13.3%) of 2,2-N3P3Az2Cl4, mp 105.5-107°. 

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Aziridinyl-Amino Substituted Cyclophosphazenes 93 Fraction 7. A mixture of 2,2,6-N4P4Az3Qs and cis-2,6-rra/w-4-N4P4Az3Cl5... 

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