Aziridines, nitrogen inversion

Table 1 Barriers to Nitrogen Inversion in Substituted Aziridines ...

Brois, S. J. (1968a) Aziridines. XI. Nitrogen inversion in N-haloaziridines. J. Amer. Chem. Soc. 90, 506-508. 

For earlier reviews on nitrogen inversion see 29>, general review 37>, nitrogen inversion in aziridines. 

Table 2. Activation parameters for pyramidal nitrogen inversion from NMR data Aziridines and substituted aziridinesa)...

Dynamic NMR and theoretical methods used to study nitrogen inversion barriers have been reviewed and data on the inversion barriers of many types of aziridines tabulated . 

Nitrogen inversion in aziridine and 2-methylaziridine was studied using H NMR by Bauer et al. [775], This study observed no dependence of the nitrogen inversion rate constant of aziridine on pressure down to a pressure of 5 torr, in sharp contrast to RRKM calculations which indicated that this system should be in the bimolecular... 

Trisubstituted atoms with a lone pair, such as amines, may undergo the process of pyramidal atomic inversion on the NMR time scale. The resonances of the two methyls in the aziridine 5-15 become equivalent at elevated temperatures through rapid nitrogen inversion. 

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