Aziridine ring ethylene derivs

The derivatives of ethylene oxide and aziridine can be used to build macrocycles. Substituted aziridine or ethylene oxide self-condenses on ring opening to form cyclic trimers, tetramers, and so on (Dale and Daasvatn, 1976 Dale et al., 1974 Hansen and Burg, 1968 Tsuboyama et al., 1970). The size of the macrocycle depends mainly on what starting material is used. In the case of N-benzylaziridine, the macrocycle formed was the tetraaza-12-crown-4. 

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