Azidirine-substituted indole

Bach reported the C2 selective alkylation of protected tryptophan via a palladium(II)-norbornene system (178, 72% yield) (13JOC12263). Azidirine-substituted indole 179 was prepared by Vedejs in 40% yield by the Stille coupling of an aziridinyl stannane with the corresponding indole (13JOC5061).The direct C2 cyanation of Al-pyrimidylindole was achieved using acetonitrile as the cyanide source with catalytic amounts of copper(II) acetate (180,70%) (13JOC9494). 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

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