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5- Azaorotic acid

Azaorotic acid as pharmaceutical, 1, 159 1 -Aza-5-oxabenzocycloheptene nomenclature, 1, 21 Azapentalenes reactions, 5, 267 Azaperone metabolism, 1, 237 Azapetine... [Pg.521]

The name 5-azaorotic acid should be given to allantoxanic (oxonic) acid but it is not yet commonly used. The elucidation of the correct structure of this compound was closely linked to the solution of the course of oxidation of uric acid mentioned earlier. [Pg.199]

C30 Cihak, A. and Sorm, F. Metabolic transformations of 5-azauracil and 5-azaorotic acid in mouse liver and Escherichia coli. Effect on the synthesis of pyrimidines. Biochem. Pharmacol., 21, 607-617 (1972)... [Pg.58]

Azaorotic (oxonic) acid represents another analogue of orotic add with cytostatic activity [274]. The drug inhibits metabolic transformation and incorporation of orotic acid in the liver and kidney [275]. Similarly to... [Pg.27]

By analogy with 5-fluoro-orotate, [270] 5-azaorotate was found to react with PRPP blocking simultaneously and in a competitive manner the phosphoribosyltransferase reaction. The newly formed 5-azaorotate 5 -phosphate and/or 5-azauridine 5 -phosphate then inhibit orotidylic acid... [Pg.27]

Dioxo-l, S,4-tetrahydro-i -iriazine-6-carhoxylic Acid 5-Azaorotic Add)... [Pg.348]

See other pages where 5- Azaorotic acid is mentioned: [Pg.159]    [Pg.159]    [Pg.1099]    [Pg.28]    [Pg.159]    [Pg.159]    [Pg.1099]    [Pg.28]    [Pg.14]    [Pg.27]    [Pg.111]   
See also in sourсe #XX -- [ Pg.199 , Pg.200 ]

See also in sourсe #XX -- [ Pg.199 , Pg.200 ]



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