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Azanaphthalenes, hydration

Following these discoveries, we have made an extensive exj)eri-mental study of covalent hydration and find it is very common, not only in the pteridine series but also in several simpler families of poly-azanaphthalenes. The methods used to diagnose this phenomenon, its... [Pg.3]

Our next step was to assess whether the methodology used to calculate hydration free energy differences for simple carbonyl-containing compounds9 was suitable for heteroaromatic bases. Since our drug design strategy entailed analysis of purine riboside hydration, a series of azanaphthalenes was initially selected for analysis in part because of their structural similarity to purines and in part because of the extensive... [Pg.369]

The first example of multiple hydration was discovered in the cation of 1,4,5,8-tetra-azanaphthalene. This species had already been recognized as undergoing hydration (see Albert Armarego,3 p. 31),... [Pg.122]

Fig. 1. The hydration of 1,4,5,8-tetra-azanaphthalene cation, as observed by proton magnetic resonance study. Fig. 1. The hydration of 1,4,5,8-tetra-azanaphthalene cation, as observed by proton magnetic resonance study.
Hydration, see also covalent hydration of azanaphthalenes, 3 ofC=Nbond, 2 consecutive, 17... [Pg.237]

See other pages where Azanaphthalenes, hydration is mentioned: [Pg.38]    [Pg.53]    [Pg.38]    [Pg.53]    [Pg.48]    [Pg.63]    [Pg.27]    [Pg.274]   
See also in sourсe #XX -- [ Pg.3 ]

See also in sourсe #XX -- [ Pg.3 ]

See also in sourсe #XX -- [ Pg.3 ]

See also in sourсe #XX -- [ Pg.3 ]



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Azanaphthalene

Azanaphthalenes

Hydration of azanaphthalenes

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