Authorization of new substances

6 Practical Guide No 1 , EC document with the reference CS/PM/2024 of 2 April 1993 and its updated version Compilation of all amendments to Practical Guide No 1 , available in English only. 

Conditions migration data (ppm) Toxicological tests required by the SCF Usual decision of the SCF 

05 3 mutagenesis tests - if results are positive use prohibited - if results are negative R = 0.05 ppm 

5-60 Full set of essential toxicological tests, unless there are good reasons for dispensing with them depends on toxicological results 

R = restriction recommended by SCF which may be expressed in a specific migration limit or a value expressed in mg/kg p.c. or in some other way. 

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