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Aureolic acid Plicamycin

Mithramycin A. (Aureolic acid, Plicamycin) [18378-89-7] M 1085.2, m 180-183°, [a]p° -51° (c 0.3, EtOH). Purified from CHCI3, and is soluble in MeOH, EtOH, Me2CO, EtOAc, Me2SO and H20, and moderately soluble in CHCI3, but is slightly soluble in C Hg and Et20. Fluorescent antitumour agent used in flowcytometry. [Thiem and Meyer TET 37 551 1981 NMR Yu et al. Nature 218 193 7965]. [Pg.496]

Members of the aureolic acid group include chromomycin A3 (42), olivomycin A (43) and mithramycin (plicamycin) (44). The aglycon of chromomycin A3 is identical to that of mithramycin, but differs from that of olivomycin A by a methyl group. Conversely, the sugar components for chromomycin A3 and olivomycin are nearly identical, while those in mithramycin are different (O Scheme 17). [Pg.2608]

Synonyms Aurelic acid Aureolic acid Mithracin Mithramycin A Mitramycin Plicamycin Chemical/Pharmaceutical/Other Class Anti-neoplastic... [Pg.1701]

See other pages where Aureolic acid Plicamycin is mentioned: [Pg.549]    [Pg.496]    [Pg.549]    [Pg.687]    [Pg.885]    [Pg.549]    [Pg.496]    [Pg.549]    [Pg.687]    [Pg.885]    [Pg.311]    [Pg.417]    [Pg.417]    [Pg.424]    [Pg.825]   
See also in sourсe #XX -- [ Pg.885 ]



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