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Aureolic acid antitumor antibiotics

Scheme 13. The antitumor antibiotics daunomycin (29 = daunorubicin) and adiiamycin (30 = doxorubicin) are polyketides with an attached deox ugar moiety. Polyketide oligodeoxy-saccharides characterized by one or more deoxysaccharide chains include the anthracyclines arugomycin (31) [73a] and viriplanin (32), the angucyclines landomycin A (see 12 in Scheme 6) and vineomycin A, (33 = P1894B [74]), and the aureolic acid antibiotics mithramycin (34) and UCH9 (35).Also,orthosomydn antibiotics, such as avUamycin A (36) can be considered as polyketide oligodeoxysaccharides... Scheme 13. The antitumor antibiotics daunomycin (29 = daunorubicin) and adiiamycin (30 = doxorubicin) are polyketides with an attached deox ugar moiety. Polyketide oligodeoxy-saccharides characterized by one or more deoxysaccharide chains include the anthracyclines arugomycin (31) [73a] and viriplanin (32), the angucyclines landomycin A (see 12 in Scheme 6) and vineomycin A, (33 = P1894B [74]), and the aureolic acid antibiotics mithramycin (34) and UCH9 (35).Also,orthosomydn antibiotics, such as avUamycin A (36) can be considered as polyketide oligodeoxysaccharides...
Antitumor antibiotics are amongst the most important of the cancer chemodierapeutic agents, which include members of the anthracycline, bleomycin, actinomycin, mitomycin and aureolic acid families. Clinically useful agents from these families are the daunomycin-... [Pg.27]

See other pages where Aureolic acid antitumor antibiotics is mentioned: [Pg.43]    [Pg.155]    [Pg.243]    [Pg.102]    [Pg.16]    [Pg.417]    [Pg.132]    [Pg.308]    [Pg.367]    [Pg.1156]   
See also in sourсe #XX -- [ Pg.3 ]



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