Attachment of Thiol End Groups

Using a convergent method of molecular alligator clip formation and attachment, the two thioesters 59 and 60 were synthesized. The aryl iodide 59 can be coupled to the alkynyl end (head) of the oligomers while the alkynyl arene 60 can be coupled to the aryl iodide end (tail) of the oligomers. Of 

We outlined the rapid syntheses of oligo(2-alkyl-l,4-phenylene-ethynylene)s via an iterative divergent/convergent approach that needed only three sets of reaction conditions for the entire iterative synthetic sequence an iodination, a protodesilylation, and a Pd/Cu-catalyzed cross coupling. The syntheses were conducted in solution and on a polymer support. At each stage in the iteration, the length of the framework doubled. Equations were derived 

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