Atrial fibrillation ablation randomized trials

Nilsson B, Chen X, Pehrson S, Kober L, Hilden J, Svendsen JH. Recurrence of pulmonary vein conduction and atrial fibrillation after pulmonary vein isolation for atrial fibrillation a randomized trial of the ostial versus the extraostial ablation strategy. Am Heart J 2006 152(3) 537.el—8. 

Wazni OM,MarroucheNF, Martin DO, etal. Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation a randomized trial. JAMA 2005 293 2634-40. 

Table 6.1 Randomized trials of atrial fibrillation ablation... 

Interventional approaches have an established role in the treatment of symptomatic patients with drug-refractory AF. Randomized trials will assess catheter ablation as first line therapy as an alternative to anti-arrhythmic drug therapy, with emphases on efficacy, safety, and survival (Table 6.1). The Radiofrequency Ablation versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (RAAFT) study is a multicenter, randomized trial designed to assess the efficacy and... 

Pappone C, Augello G, Sala S, et al. A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation the APAF Study. J Am Coll Cardiol 2006 48 2340-7. 

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