Atrazine sorbent assays

Atrazine herbicide in solution MAA MIP-based competitive inhibition assay (molecularly imprinted sorbent assay) 1 ug/ml Muldoon and Stanker, 1995... 

Muldoon, M.T. and L.H. Stanker (1995). Polymer synthesis and characterization of a molecularly imprinted sorbent assay for atrazine. J. Agric. Food Chem., 43 1424-1427. 

Schlaeppi, J-M., W. Fory, and K. Ramsteiner (1989). Hydroxyatrazine and atrazine determination in soil and water by enzyme-linked immuno-sorbent assay using specific monoclonal antibodies. J. Agric. Food Chem., 37 1532-1538. 

Molecularly imprinted sorbent assays represent one of the most typical applications of biomimetic use, where imprinted polymers are used as substitutes of natural antibodies in immunoassays. The assays usually involve competitive binding of an analyte with a certain quantity of labeled ligands, in which the labeled ligand unbound is proportional to the analyte added. Because dissociation constants of common imprinted polymers are around 10 6-10 9 M, competitive binding assays could easily be performed. In practice, many molecularly imprinted sorbent assays have been developed for biologically active compounds, including theophylline, diazepam [26], S-propranolol [27], morphine, Leu-enkephalin [28], cyclosporin A [29], yohimbine [30], methyl-a-glucoside [31], corticosteroid [32], atrazine [33, 34], and 2,4-D [35]. 

Gasc6n J, Oubina A, Barcelb D. (1997). Detection of endocrine-disrupting pesticides by enzyme-linked immuno-sorbent assay (ELISA) Application to atrazine. Trends in Analytical Chemistry 16 554-562. 

Muldoon, M.T. Stanker, L.H. Polymer synthesis and characterization of a molecularly imprinted sorbent assay for atrazine. J. Agric. Food Chem. 1995, 43, 1424-1427. Siemann, M. Andersson, L.I. Mosbach, K. Selective recognition of the herbicide atrazine by noncovalent molecularly imprinted polymers. J. Agric. Food Chem. 1996, 44, 141-145. 

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