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ATPase defect complex

Marzuki, S., Watkins, L.C. and Choo, W.M. (1989) Mitochondrial H+-ATPase in mutants of Saccharomyces cerevisiae with defective subunit 8 of the enzyme complex. Biochimica et Biophysica Acta 975, 222-230. [Pg.75]

Mitochondrial dysfunction has long been considered to play a central role in the development of cell injury during ischemia-reperfusion and hypoxia-reoxygenation [19]. Besides the inhibition of fatty acid oxidation, mitochondrial energy generation is diminished because of defects in respiratory chain function. Inhi-hition of the FO-Fl-ATPase leading to impaired function of respiratory complex I has been observed in I/R injury. Similar to ischemia, dsplatin has been shown to affed mitochondrial respiratory complexes and func-... [Pg.67]


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See also in sourсe #XX -- [ Pg.45 ]




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ATPase complex

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