Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Asymmetric reactions biologically active compounds involving

The Pictet-Spengler reaction is the method of choice for the preparation of tetrahydro-P-carbolines, which represent structural elements of several natural products such as biologically active alkaloids. It proceeds via a condensation of a carbonyl compound with a tryptamine followed by a Friedel-Crafts-type cyclization. In 2004, Jacobsen et al. reported the first catalytic asymmetric variant [25]. This acyl-Pictet-Spengler reaction involves an N-acyliminium ion as intermediate and is promoted by a chiral thiourea (general Brpnsted acid catalysis). [Pg.408]

See other pages where Asymmetric reactions biologically active compounds involving is mentioned: [Pg.82]    [Pg.323]    [Pg.193]    [Pg.193]    [Pg.45]    [Pg.235]    [Pg.147]    [Pg.3]    [Pg.70]    [Pg.2]    [Pg.815]    [Pg.2]    [Pg.249]    [Pg.213]    [Pg.352]    [Pg.402]    [Pg.99]    [Pg.116]    [Pg.281]    [Pg.101]    [Pg.99]    [Pg.443]    [Pg.326]    [Pg.278]    [Pg.1112]    [Pg.1191]    [Pg.1112]    [Pg.1191]    [Pg.185]    [Pg.103]    [Pg.281]    [Pg.3]    [Pg.77]    [Pg.1359]    [Pg.1359]    [Pg.649]    [Pg.272]   


SEARCH



Asymmetric reactions involving

Biological active compounds

Biological activity reactions

Biological compounds

Biological reaction

Biologically active compounds

© 2024 chempedia.info