Asymmetric ligands sulfinyl groups

Chiral sulfoximines liganded to copper(II) give highly enantioselective vinylogous Mukaiyama-type aldol reactions under mild conditions.137 A chiral sulfinyl group has been used to achieve 1,5- and 1,6-asymmetric induction in Mukaiyama aldols, using Yb(OTf)3 catalysis.138... 

Among /1-thiosubstituted organophosphorus compounds bearing chiral groups, phosphono methyl thiazolines (Sect. 2.2.1, Scheme 8) and o-sulfanyl aryl phos-phonamides or phosphinoxides (Sect. 3.3, schemes 20 and 21) have already been mentioned. As a complement to this, some recent synthesis of non racemic /1-sulfinyl phosphines and phosphonates and thiazolidinyl phosphonates are reported below. Moreover, some chiral )8-thio-substituted phosphines have been used as metal ligands in asymmetric catalysis and are listed in Sect. 5.3. 

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