Asthma pathogenesis

COX-2 in asthma pathogenesis and its significance in the use of selective inhibitors. Clin Exp Allergy 2002 32 339-342. 

Wei H, Zhang J, Xiao W, Feng J, Sun R, 35 Tian Z Involvement of human natural killer ceUs in asthma pathogenesis natural kiUer 2 cells in type 2 cytokine predominance. J Allergy Clin Immunol 2005 115 841-847. 

Severe Asthma Pathogenesis and Clinical Management, edited by S. J. Szefler and D. Y. M. Leung... 

Figure 27.21. Central role of effector Th2 cells in asthma pathogenesis.

Szczeklik A. Aspirin-induced asthma pathogenesis and clinical presentation. Allergy Proc 1992 13(4) 163-73. 

As noted in the discussion above, respiratory viral infections are now acknowledged as potent co-stimulants of airway inflammation in atopic children, and may be an important co-factor in driving allergic respiratory disease towards persistence. The use of recently available anti-virals in children may provide a useful prophylactic approach for reduction of the impact of these infections in asthma pathogenesis. 

Dugdale A. Non-compliance or rational decision. Lancet 1993 342 1426-1427. Rand CS, Wise RA. Adherence with asthma therapy in the management of asthma. In Szefler SJ, Leung DYM, eds. Severe Asthma Pathogenesis and Clinical Management. New York Marcel Dekker, 1996 435 64. 

Walter, M.J., and Holtzman, M.J. (2005) A centennial history of research on asthma pathogenesis. American Journal of Respiratory Cell and... 

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