Astex Therapeutics

Astex Therapeutics, 436 Cambridge Science Park, Milton Road, Cambridge CB4 OQA, UK... 

Abbott Laboratories was the first company to report NMR for fragment screening, but the technique is now widely used, particularly ligand-detected methods. Companies known to use NMR include Abbott Laboratories, Astex Therapeutics, Evotec, Schering-Plough (now Merck), and Vemalis. NMR approaches have been extensively reviewed [29, 364-5], and are also covered in more depth by Wyss and coworkers [46],... 

Acknowledgments The authors gratefully acknowledge the support of many people at Astex Therapeutics who have contributed to aspects of the work presented here. We would also like to thank Dr Chris Murray and Dr Harren Jhoti for valuable suggestions regarding the content of this chapter. 

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