Assays on Solid Support

The photograph insert shows a typical plate impregnated with substrate 17 under UV illumination after reaction of 1-gl reactions containing various lipases (columns 1-10) or controls (BSA) (columns 11 and 12) under various conditions (lanes A-L) (see the original pubhcation for details). 

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Babiak P, Reymond JL (2005) A high-throughput, low volume enzyme assay on solid support. Anal Chem 77 373-377... 

Other methods take advantage of the readiness of assays on solid support - the confinement of the substance to the bead (one-bead-one-compound) that permits a simultaneous screening of individual discrete compounds. 

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