Limit of detection assays

Different T3 immunoassays may show unexplained discrepancies between values for the same sera. Results from inter-laboratory quality assurance schemes also demonstrate a higher analytical variance for T3 than for T4 methods. Many factors have been suggested as accounting for these disparities, such as the lower quantity of T3 in sera, differences in antisera cross-reactivity, protein interferences, and different assay limits of detection. ... 

Bacterial biocatalysts incorporated on to oxygen electrodes and ISEs typically have response times to analytes of between 5 and 15 min and show good stability for 7-30 days with storage normally in buffered saline between assays. Limits of detection and detection ranges are often similar to, or overlapping with those of, enzyme-based systems, such as the examples given below. 

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