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Arylpropionamide-Derived SARMs

Scheme 4.5 Suggested dissociation pathways of the arylpropionamide-derived SARM S-22. ... Scheme 4.5 Suggested dissociation pathways of the arylpropionamide-derived SARM S-22. ...
Figure 4.9 Structures of selected SARMs androgen receptor antagonists bicalutamide (1) and flutamide (2) arylpropionamide-based agonists S-1 (3), S-4 (Andarine, 4),S-22 (5) bicyclic hydantoin-derived antagonist nilutamide (6) agonists BMS-564929 (7), and 4-(7-hydroxy-l,3-dioxo-tetrahydro-pyrroIo[l,2-c]imidazoI-2-yI)-naphthaIene-l-carbo-nitrile (8) quinolinone-based SARMs LG-121071 (9), LGD-2226 (10), and bisethyl-amino-4-trifluoromethyIquinoIin-2(lH)-one (11) and tetrahydroquinoline-derived SARMs S-40503 (12), and 2-methyI-2-(8-nitro-3a,4,5,9b-tetrahydro-3H-cycIopenta[c] chinoIin-4-yI)propan-l-oI (13). Figure 4.9 Structures of selected SARMs androgen receptor antagonists bicalutamide (1) and flutamide (2) arylpropionamide-based agonists S-1 (3), S-4 (Andarine, 4),S-22 (5) bicyclic hydantoin-derived antagonist nilutamide (6) agonists BMS-564929 (7), and 4-(7-hydroxy-l,3-dioxo-tetrahydro-pyrroIo[l,2-c]imidazoI-2-yI)-naphthaIene-l-carbo-nitrile (8) quinolinone-based SARMs LG-121071 (9), LGD-2226 (10), and bisethyl-amino-4-trifluoromethyIquinoIin-2(lH)-one (11) and tetrahydroquinoline-derived SARMs S-40503 (12), and 2-methyI-2-(8-nitro-3a,4,5,9b-tetrahydro-3H-cycIopenta[c] chinoIin-4-yI)propan-l-oI (13).

See other pages where Arylpropionamide-Derived SARMs is mentioned: [Pg.99]    [Pg.173]    [Pg.173]    [Pg.174]    [Pg.99]    [Pg.173]    [Pg.173]    [Pg.174]    [Pg.2018]    [Pg.171]    [Pg.173]   


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