Arylmanganese halide

The synthesis of biaryls involving the arylmanganese halides seems to be a very perspective approaeh and will become an extremely valuable aryl-aryl bond forming reaction. 

Enantiomerically pure a-acyloxy ketones were readily prepared by reacting alkyl, alkenyl, alkynyl and arylmanganese halides with chiral a-acyloxy carbocyclic acid chlorides (Scheme 13.22) [25]. The reaction takes place under mild conditions in ether or in TH F to give the expected ketones in high yields with an excellent enantiomeric purity. 

Functionalized alkenyl- and arylmanganese halides, prepared from alkenyl or aryl halide by halogen-lithium exchange then transmetallation, are readily acy-lated in good yields (Scheme 13.28) [30]. 

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