Aryl with aryltitanium reagents

Although the enantioselective stoichiometric addition of chiral aryltitanium reagents have been reported in 1987 [66], the catalytic enantioselective aryl addition to carbonyl compounds with titanium catalyst was realized by Walsh using the catalyst prepared from bis(sulfonamide) ligand and Ti(OTr)4 with diarylzinc as the nucleophiles, to afford the tertiary alcohol in good to excellent enantioselectivities for a range of ketone substrates [67]. Very recently, Gau reported that... 

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