Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Aromatic rings coupling with lithium reagents

Coupling of Aromatic Rings with Lithium Reagents. [Pg.110]

An analogous vinylketene intermediate (127, see Schemes 57 and 59) as proposed for the Dotz reaction has been assumed in the so-called cyclobutenedione methodology [161]. The key intermediate is a 4-aryl or 4-alkenyl substituted 2-cyclobutenone (128) that can be obtained e.g. by the reaction of the 3-cyclo-butene-1,2-dione (129) with the appropriate lithium reagent or Stille coupling with 4-chloro-3-cyclobutenone. Thermal cyclobutenone ring opening to the vinylketene 130 followed by electrocyclization furnishes the highly substituted aromatic compound 131 (see Scheme 59). [Pg.82]


See other pages where Aromatic rings coupling with lithium reagents is mentioned: [Pg.199]    [Pg.539]    [Pg.451]    [Pg.60]    [Pg.230]    [Pg.134]    [Pg.78]    [Pg.37]    [Pg.500]    [Pg.160]    [Pg.60]   
See also in sourсe #XX -- [ Pg.103 , Pg.104 ]




SEARCH



Aromatic coupling

Coupling reagent

Lithium Reagents

With aromatic rings

© 2024 chempedia.info