Aromatic Fused Dithiepines and Their -Oxides

The benzodithiepines 126 and 127 have been used as formyl and acyl anion equivalents, respectively, although the range of electrophiles was restricted to alkyl halides (75S720) and epifluorohydrin (72TL1837). The carbonyl products were formed by hydrolysis with either mercury or copper salts. 

In contrast to this, the monosulfoxide 132, readily prepared from 129 by oxidation, acts as a highly diastereoselective formyl anion equivalent and adds to 

. Shaliak,andE.D. Bergmann, Tetrahedron Lett., 1837(1972). J. L. Herrmann, J. E. Richman, and R. H. Schlessinger, Tetrahedron Lett., 2599 (1973). 

Pelter, K. Smith, R Blatcher, and S. Warren, Tetrahedron 

Medici, G. Fantin, M. Fogagnolo, and A. Dondoni, Tetrahedron Lett 24,2901(1983). 

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