Rifampicin Aripiprazole

ARIPIPRAZOLE, CLOZAPINE, HALOPERIDOL RIFABUTIN, RIFAMPICIN 1 levels of these antipsychotics t metabolism Watch for poor response to these antipsychotics consider increasing the dose... 

The manufacturers report that carbamazepine reduced the mean maximum plasma concentration and AUC of aripiprazole 30 mg by 68% and 73%, respectively. They recommend that the dose of aripiprazole is doubled when taken with carbamazepine. Other potent inducers of CYP3A4, such as efavirenz, nevirapine, phenytoin, phenobarbital, primidone, rifabutin, rifampicin and St John s wort are expected to have similar effects and an increase in the dose of aripiprazole may also be necessary if these drugs are given. ... 

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See also in sourсe #XX -- [ ]

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