Aquifex pyrophilus

D-Galacturonic acid has also been found in bacterial polysaccharides.125,126 In several Proteus O-antigens, amino acids are amide-linked to the carboxyl group of a-D-galacturonic127 or glucuronic acid.128 It has been shown that D-galacturonic acid replaces phosphate residues in the lipid A component of the lipopolysaccharide (LPS) from the bacterium Aquifex pyrophilus,129... 

Figure 12.11 Superposition of active sites from the different proteins. The active site of SmeHyuA model (gray) is compared with that of (a) aspartate racemase from Pyrococcus horikoshii (IF)LA, black) and that of (b) glutamate racemase from Aquifex pyrophilus (1B73A, black).

Huber R., Wilharm T., Huber D., Trincone A., Burggraf S., Konig H., Rachel R., Rockinger 1., Ericke H., and Stetter K. O. (1992) Aquifex pyrophilus gen. nov., sp. nov., represents a novel group of marine hyperthermophilic hydrogen-oxidizing bacteria. Syst. Appl. Microbiol. 15, 340-351. 

Klenk H-P, Meier T-D, Durovic P, Schwass V, Lottspeich F, Dennis PP, Zillig W. RNA pol5unerase of Aquifex pyrophilus implications for the evolution of the bacterial rpoBC operons and extremely thermophilic bacteria. J Mol Evol. 1999 48 528-41. 

Roberts, A., Furdui, C., Anderson, K.S. (2010) Observation of a Chemically Labile, Noncovalent Enzyme Intermediate in the Reaction of Metal-dependent Aquifex pyrophilus KD08PS by Time-resolved Mass Spectrometry. Rapid Commun. Mass Spectrom. 24 1919-1924. 

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