Aqueous solutions of biomolecules

Chapter 5 is concerned with aqueous solutions of biomolecules, particularly proteins. The emphasis is on the structural features of such solutions at the molecular (or nanometer) level and on their thermodynamic properties. 

H(f)0 effect (see Sec. 4.12.3). Although there was no hard evidence for that conjecture, the hydrophobic effect was deemed to be the most important driving force in biochemical processes. For over half of a century, the fields of aqueous solutions, in general, and aqueous solutions of biomolecules, in particular, were dominated by HcpO effects. No other competing solvent-induced effects were recognized. 

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