APTAMER-BASED BIOANALYTICAL ASSAYS AMPLIFICATION STRATEGIES

APTAMER-BASED BIOANALYTICAL ASSAYS AMPLIFICATION STRATEGIES 

Aptamers hold great promise as molecular recognition tools for their incorporation into analytical devices, and in particular, they can be used as immobilized ligands in separation technologies (Clark and Remcho, 2002), as affinity probes in capillary electrophoresis-based quantitative assays (Kotia and McGown, 2000), in affinity matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS)(Dick and McGown, 2004), and as biocomponents in biosensors (Tombelli et al., 2005). Other aptamer-based bioanalytical applications have been reviewed (Yon et al., 2003 Mukhopadhyay, 2005). 

Aptamers in Bioanalysis, Edited by Marco Mascini Copyright 2009 John Wiley Sons, Inc. 

TABLE 8.1 Overview of Aptamer-Based Bioanalytical Assays Developed for the Detection of Thrombin 

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APTAMER-BASED BIOANALYTICAL ASSAYS AMPLIFICATION STRATEGIES... 

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