Applied VS Strategies

Financial Support from the Deutsche Krebshilfe for the work on PRMT inhibitors is kindly acknowledged. 

1 Hawkins, P.C.D., Skillman, A.G., and Nicholls, A. (2006) Comparison of shapematching and docking as virtual screening tools. Journal of Medicinal Chemistry, 50, 74-82. 

2 Evers, A., Messier, G., Matter, H., and Klabunde, T. (2005) Virtual screening of biogenic amine-binding G-protein coupled receptors comparative evaluation of protein- and ligand-based virtual screening protocols. Journal of Medicinal Chemistry, 48, 5448-5465. 

3 Kirchmair,)., Laggner, C., Wolber, G., and Langer, T. (2005) Comparative analysis of protein-bound ligand conformations with respect to catalyst s conformational space subsampling algorithms. Journal of Chemical Information and Modeling, 45, 422-430. 

4 Waszkowycz, B. (2008) Towards improving compound selection in structure-based virtual screening. Drug Discovery Today, 13, 219-226. 

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