Applications and structural studies

Quinoxaline bis-A-oxides have been investigated as potential anti-cancer agents 93 06BMC6917 and anti-trypanosomal agents 94 06BMC5503 . In the latter case, a vanadyl complex was prepared in order to increase bioavailability. 

Several papers were concerned with the synthesis of and mechanism of luminescence of Cypridina luciferin and its analogues 06T6272 06TL753 06TL6057 . 

The binding of the diuretic amiloride 95 to DNA has been studied 06CC1185 . The chiral camphor-derived pyrazine ligand 96 showed monomeric coordination to Cu and Zn, in contrast to the bidentate polymeric behaviour of related earlier compounds 06ARK218 . 

The quinoxaline 100, with self-contained donor-acceptor properties, has potential in optoelectronic 06JACS10992 . Electroactive dendrimeric bis-quatemary salts have been prepared by direct quatemisation of pyrazine using dendrimeric benzyl bromides 06TL4711 . 

Albert, D. Riester, J. Osterodt, H. Wurzigcr, A, Schober, Angew. 

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