Application methods avidin-biotin molecules

Streptavidin may be immobilized to a surface using methods used with other proteins. For instance, strept(avidin) can be adsorbed onto a number of surfaces and still retain the ability to bind biotin and biotinylated molecules. Strept(avidin)-coated magnetic beads, plastic combs, and silicon chips used in many applications are made in this manner. Alternatively, streptavidin may be covalently bound to form an oriented monolayer using a cysteine derivative [101]. 

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