Aplysia toxicity

The activities of the purple fluid of the sea hare Aplysia dactylomela, such as toxic, antimicrobial and hemagglutinating properties, have been attributed to a substance of protein nature [332], Proteoglycans and adhesive glycoproteins present in the extracellular matrix of vertebrates, have also been reported in sponges. These molecules are probably involved in the cell adhesion systems of sponges [333], Recently, novel marine proteins have been reported, such as silicatein from sponge biosilica [334], and a metallothionein protein from the marine alga Fuats vesiculosus [335], Metallothioneins have also been isolated from Arctic... 

The sea hare Aplysia parvula has yielded aplyparvunin (673), which has potent fish toxicity (778). Laurencia intricata has furnished itomanallenes A (674) and B (675) the former is an epimer of the known neolaurallene (591). Chinzal-lene (676) was characterized from a Japanese Laurencia sp. (638). The stereochemistry of chinzallene is not fully established. 

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