Apicidin, synthesis

Final examples of applications of our results (91CPB1905, 99H1157) in 1-hydroxytryptophan chemistry come from the work of Boger and co-workers (99JA6197) on the synthesis of HUN 7293 (293, Scheme 46) (96MI69) and from Kitahara and co-workers (200 IHl) on the synthesis of apicidin (301) (96TL8077). 

A. Jaxa-Chamiec, P.W. Seale, P. Stead, R.J. Upton, S.L. Croft, W. Clegg, M.R. Elsegood, The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin, Bioorg. Med. Chem. Lett. 2001, 11, 773-776. 

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