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Antioxidant response element transcription factors associated with

Gene regulation by tocopherols has mainly been associated with PKC because of its deactivation by a-tocopherol and its contribution in the regulation of a number of transcription factors (NF-kappaB, API). A direct participation of the pregnane X receptor (PXR)/ retinoid X receptor (RXR) has been also shown. The antioxidant-responsive element (ARE) and the TGF-beta-responsive element appear in some cases to be implicated as well. The obser ved immunmodulatory function of a-tocopherol may also be attributed to the fact that the release of the proinflammatory cytokine interlukin-l 3 can be inhibited by a-tocopherol via... [Pg.1296]


See other pages where Antioxidant response element transcription factors associated with is mentioned: [Pg.2190]    [Pg.410]    [Pg.287]    [Pg.60]    [Pg.19]    [Pg.280]    [Pg.234]    [Pg.283]    [Pg.225]    [Pg.457]    [Pg.169]    [Pg.82]    [Pg.238]   
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Antioxidant response element

Elemental factoring

Elements with

Factor elements

Response elements

Responsibilities associated with

Responsive element

Transcription factor

Transcription response elements

Transcriptional factor

Transcriptional responses

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