Antimicrobial sceptrin

The fungicidal activity of sceptrin at 10 ppm was found to be >65 % inhibition of Phytophthora infestans (potato late blight) [103]. In addition to its antimicrobial, antiviral [104], antimuscarinic [22], and antihistaminic [30] properties, sceptrin was shown to be the first and most potent nonpeptide somatostatin inhibitor in the submicromolar range [105]. 

Walker, Roger P., Faulkner, D. John, Van Engen, Donna, Clardy, Jon., (1981). Sceptrin, an antimicrobial agent from the sponge Agelas sceptrum. J. Am. Chem. Soc. 103, 6772-6773. 

Beman, V. S., Roll, D. M., Ireland, Chris M., Greenstein, M., Maiese, William M., Steinberg, D. A., (1993). A study on the mechanism of action of sceptrin, an antimicrobial agent isolated from the South Pacific sponge Agelas mauritiana. J. Antimicrob. Chemother. 32, 539-550. 

Walker RP, Faulkner DJ, VanEngen D, Clardy J (1981) Sceptrin, an antimicrobial agent from the spongesceptrum. J Am Chem Soc 103 6772-6773... 

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